What do I think is the best weapon? Whichever one I happen to be using to kill things with.
Oh, and be warned: whenever anyone brings up the subject of “the best weapon in the game” or some such, this guy usually springs to mind.
: My personal favorite is the missile launcher. Though not very useful and
: often suicidal in close ranges, it is my favorite weapon to use at a
: distance, especially with groups of weak enemies and/or a tough one. I
: don't really recall any enemies that are all that fast (at least at the
: difficulty level I'm currently playing at), and you can pretty much hit
: them almost all of the time if you aim a little distance away from where
: they are facing (assuming they are moving), or otherwise you could simply
: pick em' off stationary.